Outputs

Project scope includes building 35 clinical Business Use Cases, implementing 5 priority data categories across 9 implementation and demonstration countries; Real-world deployments proving the European EHR Exchange Format works — in production clinical environments.

Five priority EEHRxF data categories

i2X implements 5 priority data categories defined by the European Health Data Space regulation, using the corresponding EU FHIR implementation guides - published and maintained through the MyHealth@EU programme.

Patient Summary

EU PS IG · HL7 IPS

A minimal but clinically relevant data set — allergies, medications, current diagnoses, relevant history — that travels with the patient for unplanned and emergency care across EU borders.

WP4 · Task 4.1FHIR R4

ePrescription

EU eP IG · FHIR R4

Electronic prescriptions and dispensation records that can be validated and fulfilled at pharmacies across any EU member state, regardless of a country's National ePrescription System.

WP4 · Task 4.2FHIR R4

Laboratory Results

EU Lab IG · FHIR R4

Structured laboratory reports —Complete Blood-Count (CBC), biochemistry tests and microbiology tests— shared in a standardised format any clinician or automated system in another member state can interpret without manual re-entry.

WP5 · Task 5.1FHIR R4

Medical Imaging

EEHRxF Imaging · DICOM

Radiology imaging and structured radiology reports accessible across borders at full diagnostic quality, providing specialist consultations and second opinions without physical media or shipping services.

WP5 · Task 5.2FHIR + DICOM

Hospital Discharge Reports

EU HDR IG · FHIR R4

Complete clinical handover documents (diagnosis, procedures, prescribed medication upon discharge, and follow-up instructions) transferred between providers across borders so post-discharge care can begin immediately.

WP5 · Task 5.3FHIR R4
All five categories align with the MyHealth@EU technical specifications and the EEHRxF Annex of the EHDS Regulation. All implementations use FHIR R4 profiles published by HL7 Europe and maintained through the formal EEHRxF specification governance process.

EEHRxF Testing and Implementation Lab

One of the project's objectives is to establish the conformance testing infrastructure that ensures every implementation and demonstration system meets the EEHRxF specifications before patient data cross national borders. IHE Catalyst and the Department of Health Ireland, co-leaders of WP3, use:

Conformance Testing

Automated validation of vendor implementations against EU FHIR implementation guides. Every system must pass structured conformance checks before joining any clinical implementation and demonstration site deployment.

Plugathons

Multi-day interoperability testing events modelled on IHE Connectathons, where vendors, national contact points, and implementation and demonstration teams test end-to-end data exchange across systems and countries in real time.

Implementation Guide Validation

Continuous tooling that validates clinical content against EU FHIR profiles, business rules, and value sets — detecting any specification drift before it reaches production systems deployed in real clinical environments.

How a plugathon works

Registration and pre-testing

Vendor systems complete self-attestation and pre-validation against published FHIR profiles using the conformance toolkit provided by WP3, before the event begins.

Live interoperability testing

Systems from different vendors and member states exchange synthetic patient records — across all five priority categories — under structured test scenarios managed by the WP3 team.

Gap analysis and specification feedback

Each system receives a conformance report detailing any deviations. Vendors and IG maintainers use findings to improve both implementations and specifications.

Certification, implementation & demonstration clearance

Systems that meet all conformance criteria receive a certificate and are cleared to participate in clinical implementation and demonstration handling real patient data under EHDS data governance rules.

35 clinical Business Use Cases across 9 countries and 16 sites

Spanning hospitals, primary care centres, pharmacies, radiology units, and laboratory networks across Europe — not controlled pilot environments — where EEHRxF is deployed and validated against real clinical workflows and patient populations.

35
Clinical Business Use Cases
5
Priority EEHRxF data categories
9
Implementation & demonstration countries
16
Implementation & demonstration sites
3M+
Citizens & patients reached
1,200+
Healthcare professionals engaged
32+
Healthcare IT systems adapted
Portugal
Lead country
Greece
Implementing
Italy
Implementing
Spain
Implementing
Finland
Implementing
Sweden
Implementing
Belgium
Implementing
Germany
Implementing
Romania
Implementing
Norway
Implementing

Clinical use cases driving implementation

We mapped each use case on a real clinical scenario linked to one or more EEHRxF data categories, a set of implementation and demonstration sites, and measurable outcomes for patients and the clinicians who care for them.

Cross-border emergency

EU citizen receives emergency care abroad. The treating clinician retrieves their Patient Summary (allergies, medication, and diagnoses) from the home-country EHR in seconds, without phone calls.

Foreign pharmacy dispensation

Patient fills a prescription at a pharmacy in a different EU member state. The pharmacist validates and dispenses using the EU ePrescription, without re-prescribing or contacting the original prescriber.

Specialist referral with lab results

Chronic disease patient is referred to a specialist in another country. Structured lab results travel with the referral as EU Lab IG documents, preventing duplicate testing and delay at the specialist appointment.

Remote radiology second opinion

Imaging study and structured report sent to a specialist abroad for a second opinion. Full-quality DICOM images travel with the FHIR radiology report — without physical media or shipping services.

Discharge continuity across borders

Patient hospitalised abroad returns home. The EU Discharge Report is already available to local GPs — covering diagnosis, procedures, medications, and follow-up — before the patient walks through the door.

Explore further

Meet the teams building this

38 partners across 12 EU Member States - national contact points, hospitals, vendors, standards bodies, and research institutions - making EEHRxF real in clinical settings.